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Article

Stemness Landscape and Its Clinical Implications in Hepatocellular Carcinoma

2023-07-03

Abstract excerpt

<h4>Background: </h4> It is generally accepted that hepatocarcinoma(HCC) originates from cancer stem cells (CSCs), which are responsible for HCC progression, metastasis and therapy resistance. The high heterogeneity of CSCs has precluded clinical application of CSC-targeting therapy. Here, we aimed to characterize the stemness landscapes and screen for certain patients more responsive to immunotherapy. <h4>Method...

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Literature Corpus work
15e1eb6b-0091-5ab2-894e-2a6182c2fa18
DOI
10.21203/rs.3.rs-3063827/v1
Open publication

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