Article

Serological Proteome Analysis (SERPA) Reveals Breast Cancer-Associated Autoantibodies Targeting Placental Antigens

2026-08-06

Abstract excerpt

<title>Abstract</title> <p>Background The association between placental development and cancer formation was first proposed over a hundred years ago. In our current investigation, we pioneered the application of serological proteome analysis (SERPA) of human placental proteins to detect tumor-associated antigens that trigger autoimmune responses in breast cancer patients. Methods We employed SERPA to examine se...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: edc130d3-ec9d-5cb3-bbf0-e16924eb6ebc
DOI: 10.21203/rs.3.rs-10289101/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Serological Proteome Analysis (SERPA) Reveals Breast Cancer-Associated Autoantibodies Targeting Placental AntigensDOI 10.21203/rs.3.rs-10289101/v1Read

Characterization of the tumor immune microenvironment in pregnancy-associated breast cancer through multiplex immunohistochemistry and transcriptome analysesSemantic proximity Read

Breast cancer proteomics: a review for cliniciansSemantic proximity Read

ctDNA in Breast Milk for Early Detection of Pregnancy Associated Breast CancerSemantic proximity Read

Sensitive and Specific Early-Stage Breast Cancer Detection using Deep Proteome Profiling from PlasmaSemantic proximity Read

Determination of biomarker candidates for the placenta accreta spectrum by plasma proteomic analysisSemantic proximity Read

Molecular characterization of pregnancy-associated breast cancer and insights on timing from GEICAM-EMBARCAM studySemantic proximity Read

Profiling protein post-translational modifications in plasma-derived extracellular vesicles as fingerprints for breast cancer subtypesSemantic proximity Read

Decoding the Circulating Proteome: Matrix and Immune Context Markers Shape Early Multi-Cancer DetectionSemantic proximity Read

Breast Cancer Cell Secretome Analysis to Decipher miRNA Tumor Biology and Discover Potential BiomarkersSemantic proximity Read

Identification of lipid droplet-associated genes in breast cancer patientsSemantic proximity Read

A List of Candidate Cancer Biomarkers for Targeted ProteomicsSemantic proximity Read

Detergent-Insoluble Proteome Analysis Revealed Aberrantly Aggregated Proteins in Human Preeclampsia PlacentasSemantic proximity Read