Characterization of the tumor immune microenvironment in pregnancy-associated breast cancer through multiplex immunohistochemistry and transcriptome analyses

Abstract excerpt

Abstract Background Pregnancy-associated breast cancer (PABC) is breast cancer diagnosed during pregnancy or within 2 years postpartum. Although relatively rare, it is associated with a poor prognosis, and the underlying mechanisms contributing to this unfavorable condition remain incompletely understood. In this study, we investigated tumor microenvironmental features linked to pregnancy and lactation in an...

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