Article

Breast Cancer Cell Secretome Analysis to Decipher miRNA Tumor Biology and Discover Potential Biomarkers

2022-02-07

Abstract excerpt

MicroRNA (miRNA/miR) miR526b and miR655 overexpressed tumor cell free secretions promote breast cancer phenotypes in the tumor microenvironment (TME). However, the mechanisms of miRNA regulating TME have never been investigated. With mass spectrometry analysis of MCF7-miRNA-overexpressed versus miRNA-low MCF7-Mock tumor cell secretomes we identified 34 novel secretory proteins coded by eight genes YWHAB, TXNDC12,...

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Literature Corpus work: 3eb2e286-76b8-574e-a9e1-1ccdd5ad5efb
DOI: 10.21203/rs.3.rs-1328838/v1

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