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Article

Investigation of the function of LMTK3 in breast cancer invasion and transcriptional regulation

2015-01-01

Abstract excerpt

The role of Lemur tyrosine kinase 3 (LMTK3) and its association with cell proliferation and endocrine resistance in breast cancer due to its ability of regulating estrogen receptor α (ERα) has been previously addressed in our laboratory. However, the ER-independent function of LMTK3 has not been studied yet. We found that LMTK3 promotes the development of a metastatic phenotype by inducing the expression of genes...

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Literature Corpus work
ed87bca2-1b4f-5770-bf31-a3ea4ba810cd
DOI
10.25560/26991
Open publication

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