Article

Isolation of high yield and quality RNA from human precision-cut lung slices for RNA-sequencing and computational integration with larger patient cohorts

2020-08-22

Abstract excerpt

Precision-cut lung slices (PCLS) have gained increasing interest as a model to study lung biology and disease, as well as for screening novel therapeutics. In particular, PCLS derived from human tissue can better recapitulate some aspects of lung biology and disease as compared to PCLS derived from animals ( e.g. clinical heterogeneity), but access to human tissue is limited. A number of different experimental re...

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Literature Corpus work: ed7f1d10-5e26-5422-b1b9-9e6bf43ef706
DOI: 10.1101/2020.08.21.254516

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