Article
miRNA Profiling in Human Precision-cut Lung Slices (PCLS))
2021-03-31
Abstract excerpt
<title>Abstract</title> <p>ObjectiveHuman precision cut lung slices (PCLS) are widely used as an ex vivo model system for drug discovery and development of new therapies. PCLS reflect the functional heterogeneity of lung tissue and possess relevant lung cell types. We thus determined the use of PCLS in studying non-coding RNAs notably miRNAs, which are important gene regulatory molecules. Since miRNAs play key ro...
Topics
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- Extracellular vesicles in disease
- Inhalation and Respiratory Drug Delivery
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Liver physiology and pathology
- MicroRNA in disease regulation
- Neonatal Respiratory Health Research
- Occupational and environmental lung diseases
- Respiratory viral infections research
Identifiers and source
- Literature Corpus work
- 5d1ac868-c45a-5061-8bbf-e6f9116b0242
- DOI
- 10.21203/rs.3.rs-362859/v1
