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PTEN overexpression and nuclear beta-catenin stabilization promote morular differentiation through induction of epithelial-mesenchymal transition and cancer stem cell-like properties in endometrial carcinoma

2022-09-16

Abstract excerpt

<h4>Background: </h4> Although a lack of functional PTEN contributes to tumorigenesis in a wide spectrum of human malignancies, little is known about the functional role of its overexpression in the tumors. The current study focused on PTEN overexpression in endometrial carcinoma (Em Ca). <h4>Methods: </h4> The functional impact of PTEN overexpression was assessed by Em Ca cell lines. Immunohistochemical analyses...

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Literature Corpus work
ed79a4a5-ac29-5f10-9201-2ecac2f54d28
DOI
10.21203/rs.3.rs-2059866/v1
Open publication

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PTEN overexpression and nuclear beta-catenin stabilization promote morular differentiation through induction of epithelial-mesenchymal transition and cancer stem cell-like properties in endometrial carcinomaDOI 10.21203/rs.3.rs-2059866/v1
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