Back to search

Article

Proteogenomic Landscape of Gastric Adenocarcinoma Peritoneal Metastases

2020-10-05

Abstract excerpt

<title>Abstract</title> <p>Advanced gastric adenocarcinoma (GAC) often leads to peritoneal carcinomatosis (PC) and is associated with very poor outcomes. Therapeutic are limited and effective. Here we report the first proteogenomic study of PC cells from a prospective GAC cohort (n = 26 patients). A total of 16,449 proteins were detected from whole cell extracts (TCEs). PC cells could be classified based on the p...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
ed63eb90-2926-5821-9326-8e7822e2cdc9
DOI
10.21203/rs.3.rs-81037/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Proteogenomic Landscape of Gastric Adenocarcinoma Peritoneal MetastasesDOI 10.21203/rs.3.rs-81037/v1
Gastric Cancer with Ovarian Metastasis Exhibits Distinct Transcriptomic and Pharmacogenomic Signatures Revealing Immune Metabolic VulnerabilitiesSemantic proximity
Proteogenomic landscape of human pancreatic ductal adenocarcinoma in an Asian population reveals tumor cell-enriched and immune-rich subtypesSemantic proximity
Comprehensive immunophenotyping of gastric adenocarcinoma identifies an inflamed class of tumors amenable to immunotherapiesSemantic proximity
Cancer-Testis Antigens as Clinical and Prognostic Biomarkers in Gastric Adenocarcinoma: Integration of Differential Expression, Clinical Associations, Survival, and Co-Expression NetworksSemantic proximity
A proteomic landscape of diffuse-type gastric cancer.Semantic proximity
Integration of proteogenomic analyses in esophageal squamous cell carcinomaSemantic proximity
EXPRESSION INSIGHTS INTO GASTRIC ADENOCARCINOMA: NETWORK ANALYSIS REVEALS KEY HUB GENES AND FUNCTIONAL MODULESSemantic proximity
Unraveling the Unfolded Protein Response Signature: Implications for Tumor Immune Microenvironment Heterogeneity and Clinical Prognosis in Stomach CancerSemantic proximity
Proteomic Heterogeneity of the Extracellular Matrix Identifies Histologic Subtype-Specific Fibroblast in Gastric CancerSemantic proximity
Complement system-related genes in stomach adenocarcinoma: Prognostic signature, immune landscape, and drug resistanceSemantic proximity
A Stromal-Immune Gene Signature for Precision Prognosis and Therapeutic Guidance in Gastric CancerSemantic proximity
Genetic alterations and their clinical implications in gastric cancer peritoneal carcinomatosis revealed by whole-exome sequencing of malignant ascites.Semantic proximity
Select a neighboring publication to make it the new centre.