A proteomic landscape of diffuse-type gastric cancer.

doi:10.1038/s41467-018-03121-2

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Article

A proteomic landscape of diffuse-type gastric cancer.

Nature communications - 8 Mar 2018

Ge Sai, Xia Xia, Ding Chen, Zhen Bei, Zhou Quan, Feng Jinwen, Yuan Jiajia, Chen Rui, Li Yumei, Ge Zhongqi, Ji Jiafu, Zhang Lianhai, Wang Jiayuan, Li Zhongwu, Lai Yumei, Hu Ying, Li Yanyan, Li Yilin, Gao Jing, Chen Lin, Xu Jianming, Zhang Chunchao, Jung Sung Yun, Choi Jong Min, Jain Antrix, Liu Mingwei, Song Lei, Liu Wanlin, Guo Gaigai, Gong Tongqing, Huang Yin, Qiu Yang, Huang Wenwen, Shi Tieliu, Zhu Weimin, Wang Yi, He Fuchu, Shen Lin, Qin Jun

Abstract excerpt

The diffuse-type gastric cancer (DGC) is a subtype of gastric cancer with the worst prognosis and few treatment options. Here we present a dataset from 84 DGC patients, composed of a proteome of 11,340 gene products and mutation information of 274 cancer driver genes covering paired tumor and nearby tissue. DGC can be classified into three subtypes (PX1-3) based on the altered proteome alone. PX1 and PX2 exhibit...

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PMID: 29520031
DOI: 10.1038/s41467-018-03121-2
PMCID: PMC5843664

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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