Gastric Cancer with Ovarian Metastasis Exhibits Distinct Transcriptomic and Pharmacogenomic Signatures Revealing Immune Metabolic Vulnerabilities

Abstract excerpt

<title>Abstract</title> <p>Ovarian metastasis from gastric cancer (GOM) represents a rare but clinically significant condition that poses major diagnostic and therapeutic challenges. Often misclassified as primary ovarian cancer (OC) due to morphological and anatomical similarities, GOM may be subjected to inappropriate treatment regimens that do not reflect its true biological characteristics. To address this ga...

Topics

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• Clonal Evolution
• Gastric Cancer Management and Outcomes
• Gene Expression Profiling
• Gene Expression Regulation, Neoplastic
• Mutation
• Peritoneal Neoplasms
• Stomach Neoplasms
• Transcriptome

Identifiers and source

Literature Corpus work

2ce64323-03a4-5f19-895e-196f60fc1114

DOI

10.21203/rs.3.rs-7863401/v1