Article

Characterization of SN38-Resistant T47D Breast Cancer Cell Sublines Overexpressing BCRP, MRP1, MRP2, MRP3, and MRP4

2021-01-12

Abstract excerpt

<h4>Background: </h4> Although several novel resistant breast cancer cell lines have been established, only a few resistant breast cancer cell lines overexpress breast cancer resistance proteins (BCRP). The aim of this study was to establish new resistant breast cancer cell lines overexpressing BCRP using SN38 (7-ethyl-10-hydroxycamptothecin), an active metabolite of irinotecan and was to discover genes and mechan...

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Literature Corpus work: ed607dd9-d8d1-544c-8575-898a90af94ca
DOI: 10.21203/rs.3.rs-141966/v1

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Characterization of SN38-Resistant T47D Breast Cancer Cell Sublines Overexpressing BCRP, MRP1, MRP2, MRP3, and MRP4DOI 10.21203/rs.3.rs-141966/v1Read

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