Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A multidrug resistance transporter from human MCF-7 breast cancer cells

22 Dec 1998

Abstract excerpt

MCF-7/AdrVp is a multidrug-resistant human breast cancer subline that displays an ATP-dependent reduction in the intracellular accumulation of anthracycline anticancer drugs in the absence of overexpression of known multidrug resistance transporters such as P glycoprotein or the multidrug resistance protein. RNA fingerprinting led to the identification of a 2.4-kb mRNA that is overexpressed in MCF-7/AdrVp cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Transport and Resistance Mechanisms
Share to Pharmacological Effects and Toxicity Studies
Share to Trace Elements in Health

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9861027
DOI: 10.1073/pnas.95.26.15665

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A multidrug resistance transporter from human MCF-7 breast cancer cellsPMID 9861027Read ↗

Atypical Multidrug Resistance: Breast Cancer Resistance Protein Messenger RNA Expression in Mitoxantrone-Selected Cell LinesSemantic proximity Read ↗

Reduced drug accumulation and multidrug resistance in human breast cancer cells without associated P-glycoprotein or MRP overexpression.Semantic proximity Read ↗

Breast cancer resistance protein (BCRP/ABCG2): its role in multidrug resistance and regulation of its gene expressionSemantic proximity Read ↗

Expression of the mutated p53 tumor suppressor protein and its molecular and biochemical characterization in multidrug resistant MCF-7/Adr human breast cancer cellsSemantic proximity Read ↗

Structure and Function of the Human Breast Cancer Resistance Protein (BCRP/ABCG2)Semantic proximity Read ↗

A mutation hot spot in the Bcrp1 (Abcg2) multidrug transporter in mouse cell lines selected for Doxorubicin resistance.Semantic proximity Read ↗

Impact of breast cancer resistance protein on cancer treatment outcomes.Semantic proximity Read ↗

Not only P-glycoprotein: Amplification of the ABCB1-containing chromosome region 7q21 confers multidrug resistance upon cancer cells by coordinated overexpression of an assortment of resistance-related proteins.Semantic proximity Read ↗

ABCB1/MDR1 contributes to the anticancer drug-resistant phenotype of IPH-926 human lobular breast cancer cells.Semantic proximity Read ↗

Human breast cancer MCF-7 cell line contains inherently drug-resistant subclones with distinct genotypic and phenotypic features.Semantic proximity Read ↗

Breast cancer resistance protein (BCRP/ABCG2).Semantic proximity Read ↗

Epigenetic and Cellular Reprogramming of Doxorubicin-Resistant MCF-7 Cells Treated with CurcuminSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.