Article
Tamoxifen resistance induction results in mitoxantrone resistance in MCF-7 breast cancer cells via upregulation of ABCG2 expression
2023-03-02
Abstract excerpt
One of the important barriers in the treatment of breast cancer is the development of tamoxifen resistance. Different mechanisms underlying tamoxifen resistance were identified. In this thesis, we aimed to assess the effect of tamoxifen resistance induction on ABCG2 gene/protein expression level and function in the parent MCF-7 breast cancer cell line and its tamoxifen-resistant (MCF-7/TAMR) cell line. The ABCG2 m...
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Identifiers and source
- Literature Corpus work
- 82521702-138a-51a2-9566-26099af5ff28
- DOI
- 10.21203/rs.3.rs-2627530/v1