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Cytogenetic and molecular analysis of the acute monocytic leukemia cell line THP-1 with anMLL-AF9 translocation

2000-01-01

Abstract excerpt

Cell lines derived from patients with leukemia are used in many molecular biology studies. Here we report the cytogenetic analysis of the THP-1 cell line using G-banding, fluorescence in situ hybridization (FISH), and spectral karyotyping (SKY), and the molecular characterization of the MLL-AF9 rearrangement by RT-PCR. The THP-1 cell line was established from the peripheral blood of a 1-year-old boy with acute mon...

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Literature Corpus work
ed480433-d6bd-534b-8787-d83815e60fdb
DOI
10.1002/1098-2264(2000)9999:9999<::aid-gcc1040>3.0.co;2-z
Open publication

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Cytogenetic and molecular analysis of the acute monocytic leukemia cell line THP-1 with anMLL-AF9 translocationDOI 10.1002/1098-2264(2000)9999:9999<::aid-gcc1040>3.0.co;2-z
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