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Article

Rapid Screening of Leukemia Fusion Transcripts in Acute Leukemia by Real-time PCR

1 Jan 2002

Abstract excerpt

We established a real-time PCR method that can simultaneously detect 10 different fusion transcripts (major, minor and micro BCR/ABL, AML1/MTG8, PML/RARalpha, CBFbeta/MYH11, TEL/AML1, E2A/PBX1, MLL/AF4, and MLL/AF9) together with Wilms' tumor gene (WT1) transcripts. This screening method allowed the processing of six specimens concomitantly and required only one working day from RNA extraction to final results....

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PMID: 12613515
DOI: 10.1080/1042819021000040206

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