Article

A unique spliced varicella-zoster virus latency transcript represses expression of the viral transactivator gene 61

2017-08-10

Abstract excerpt

During primary infection, neurotropic alphaherpesviruses (αHVs) gain access to neurons in sensory and cranial ganglia establishing lifelong latent infection from which they can later reactivate to cause debilitating disease 1 . For most αHVs, including the best-studied herpes simplex type 1 ( HSV-1), viral latency is characterized by expression of a single or restricted set of transcripts that map antisense to th...

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Literature Corpus work: ed3dc9c1-aac6-5852-a328-7f2f231deb85
DOI: 10.1101/174797

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