Article

<i>SLCO5A1</i> and synaptic assembly genes contribute to impulsivity in juvenile myoclonic epilepsy

2022-04-21

Abstract excerpt

<h4>Introductory Paragraph</h4> Elevated impulsivity is a key component of attention-deficit hyperactivity disorder (ADHD), bipolar disorder and epilepsy 1-5 . We performed a genome-wide association, colocalization and pathway analysis of impulsivity in juvenile myoclonic epilepsy (JME). We identify genome-wide associated SNPs at 8q13.3 (p=7.5 × 10 −9 ) and 10p11.21 (p=3.6 × 10 −8 ). The 8q13.3 locus colocalizes w...

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Literature Corpus work: ed0921ad-b597-52a5-8810-69dd91064baa
DOI: 10.1101/2022.04.19.22273994

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