Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SLCO5A1 and synaptic assembly genes contribute to impulsivity in juvenile myoclonic epilepsy

28 Sept 2023

Abstract excerpt

Abstract Elevated impulsivity is a key component of attention-deficit hyperactivity disorder (ADHD), bipolar disorder and juvenile myoclonic epilepsy (JME). We performed a genome-wide association, colocalization, polygenic risk score, and pathway analysis of impulsivity in JME ( n = 381). Results were followed up with functional characterisation using a drosophila model. We identified genome-wide associated SNPs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epilepsy research and treatment
Share to Genetics and Neurodevelopmental Disorders
Share to Glycogen Storage Diseases and Myoclonus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37770509
DOI: 10.1038/s41525-023-00370-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SLCO5A1 and synaptic assembly genes contribute to impulsivity in juvenile myoclonic epilepsyPMID 37770509Read ↗

<i>SLCO5A1</i> and synaptic assembly genes contribute to impulsivity in juvenile myoclonic epilepsySemantic proximity Read ↗

Intellectual Disability-related genes increase ADHD risk and locomotor activity in <i>Drosophila</i>Semantic proximity Read ↗

Exome chip analyses in adult attention deficit hyperactivity disorder.Semantic proximity Read ↗

Autism-associated <i>SCN2A</i> deficiency disrupts cortico-striatal circuitry in human brain assembloidsSemantic proximity Read ↗

Whole exome sequencing in ADHD trios from single and multi-incident families implicates new candidate genes and highlights polygenic transmission.Semantic proximity Read ↗

Integrated genome-wide association study findings: identification of a neurodevelopmental network for attention deficit hyperactivity disorder.Semantic proximity Read ↗

Genetic mosaicism, intrafamilial phenotypic heterogeneity, and molecular defects of a novel missense SLC6A1 mutation associated with epilepsy and ADHD.Semantic proximity Read ↗

Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS.Semantic proximity Read ↗

Rare Synaptogenesis-Impairing Mutations in SLITRK5 Are Associated with Obsessive Compulsive Disorder.Semantic proximity Read ↗

Contribution of Intellectual Disability–Related Genes to ADHD Risk and to Locomotor Activity in DrosophilaSemantic proximity Read ↗

Polygenic risk score-based phenome-wide association study identifies novel associations for Tourette syndromeSemantic proximity Read ↗

Polygenic risk score-based phenome-wide association study identifies novel associations for Tourette syndromeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.