Article

Integrity assay for messenger RNA in mouse and human brain samples and synaptosomal preparations

2024-01-12

Abstract excerpt

Traditionally, RNA integrity evaluation is based on ribosomal RNAs (rRNAs). Nevertheless, gene expression studies are usually focused on protein coding messenger RNAs (mRNAs). As rRNA and mRNA have significant structural and functional differences, the assumption that rRNA integrity properly represents mRNA integrity may not be accurate. Moreover, contrary to whole tissue RNA samples, subcellular preparations such...

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Literature Corpus work: ecf559e6-e811-56b1-8e0c-fee92b5af062
DOI: 10.1101/2024.01.12.575353

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