Article

Automated chromatin profiling with spa-ChIP-seq uncovers the impacts of condition variations

2025-08-19

Abstract excerpt

<h4>ABSTRACT</h4> Chromatin immunoprecipitation followed by sequencing (ChIP-seq) is widely used to study the genomic localization of DNA-associated proteins. However, conventional protocols include multiple manual steps that can introduce inconsistency and limit scalability, thereby restricting the inclusion of appropriate replicates and controls. Although the introduction of liquid handling platforms has improv...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ecf41c6b-d851-5500-9d19-1f81403f8cef
DOI: 10.1101/2025.08.14.670415

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Automated chromatin profiling with spa-ChIP-seq uncovers the impacts of condition variationsDOI 10.1101/2025.08.14.670415Read

High throughput genome-wide single cell protein:DNA binding site mapping by targeted insertion of promoters (TIP-seq)Semantic proximity Read

Multifactorial chromatin regulatory landscapes at single cell resolutionSemantic proximity Read

A ChIP-exo screen of 887 PCRP transcription factor antibodies in human cellsSemantic proximity Read

ChIP-Atlas 3.0: a data-mining suite to explore chromosome architecture together with large-scale regulome data.Semantic proximity Read

A highly parallel, automated platform enabling individual or sequential ChIP of histone marks and transcription factorsSemantic proximity Read

Single-cell mapping of regulatory DNA:Protein interactionsSemantic proximity Read

txci-ATAC-seq, a massive-scale single-cell technique to profile chromatin accessibilitySemantic proximity Read

SNP-ChIP: A versatile and tag-free method to quantify changes in protein binding across the genomeSemantic proximity Read

HyDrop v2: Scalable atlas construction for training sequence-to-function modelsSemantic proximity Read

To mock or not: a comprehensive comparison of mock IP and DNA input for ChIP-seqSemantic proximity Read

Interactive design and validation of antibody panels using single-cell RNA-seq atlasesSemantic proximity Read

Ultra-parallel ChIP-seq by barcoding of intact nucleiSemantic proximity Read