Article

A highly parallel, automated platform enabling individual or sequential ChIP of histone marks and transcription factors

2019-08-07

Abstract excerpt

Despite its popularity, chromatin immunoprecipitation followed by sequencing (ChIP-seq) remains a tedious (>2d), manually intensive, low-sensitivity and low-throughput approach. Here, we combine principles of microengineering, surface chemistry and molecular biology to address the major limitations of standard ChIP-seq. The resulting approach, FloChIP, automates and miniaturizes ChIP in a beadless fashion while fa...

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Literature Corpus work: 3ce28b75-44ad-50c0-8aca-9835dae15d10
DOI: 10.1101/728634

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