Article

Acetylation of cytidine residues boosts HIV-1 gene expression by increasing viral RNA stability

2020-01-31

Abstract excerpt

Covalent modifications added to individual nucleotides on mRNAs, called epitranscriptomic modifications, have recently emerged as key regulators of both cellular and viral mRNA function 1,2 and RNA methylation has now been shown to enhance the replication of human immunodeficiency virus 1 (HIV-1) and several other viruses 3–11 . Recently, acetylation of the N 4 position of cytidine (ac4C) was reported to boost...

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Literature Corpus work: ece7bd4f-312d-59de-bf2d-3f712d5e19b1
DOI: 10.1101/2020.01.31.925578

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