Article

Suppression of MyD88 disturbs gut microbiota and activates NLRs pathway hence fails to ameliorate DSS-induced colitis

2022-12-14

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> The interaction between gut microbiota and innate immunity plays an important role in the pathogenesis of inflammatory bowel disease (IBD). Myeloid differentiation factor 88 (MyD88) is the core adaptor for Toll-like receptors (TLRs) defending against microbial invasion and initiating downstream immune response during microbiota-host interaction. However, the rol...

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Literature Corpus work: ec9fbd36-018d-5627-b900-5fa27d01f269
DOI: 10.21203/rs.3.rs-2361141/v1

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