Article
Innate immune activation in intestinal homeostasis.
Journal of innate immunity - 1 Jan 2011
Harrison Oliver J, Maloy Kevin J
Abstract excerpt
Loss of intestinal immune regulation leading to aberrant immune responses to the commensal microbiota are believed to precipitate the chronic inflammation observed in the gastrointestinal tract of patients with inflammatory bowel diseases (IBD), Crohn's disease and ulcerative colitis. Innate immune receptors that recognize conserved components derived from the microbiota are widely expressed by both epithelial...
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