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Neutrophils in cancer development and progression: Roles, mechanisms, and implications (Review)

7 Jul 2016

Abstract excerpt

Neutrophils are predominant immune cells that protect the host from microbial infection. The roles of neutrophils in tumor have long been ignored due to their short life span and terminal differentiation phenotype. In recent years, emerging evidence indicates that neutrophils have phenotypic and functional plasticity. Neutrophils eliminate malignant cells by releasing the antimicrobial and cytotoxic contents in...

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PMID: 27573431
DOI: 10.3892/ijo.2016.3616

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