Article

Infarct Border-Zone Biomechanics After Myocardial Infarction: Linking Mechanotransduction, Fibrosis, and Ventricular Dysfunction

2026-02-28

Abstract excerpt

Myocardial infarction (MI) transforms the left ventricle into a mechanically heterogeneous, evolving composite in which necrotic scar, viable myocardium, edema, microvascular injury, and fibro-inflammatory remodeling coexist. The infarct border zone is the decisive interface of this composite: a region in which surviving myocytes and stressed extracellular matrix (ECM) share load, exchange signals, and progressive...

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Literature Corpus work: ec28c678-7b34-564e-94c6-e99c48210ca1
DOI: 10.20944/preprints202602.1920.v1

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