Article

Full-Field Analysis Indicates Late Reperfusion Therapy Broadens and Mechanically Smooths the Borderzone During Post-Infarction Inflammation

2025-09-07

Abstract excerpt

Late reperfusion therapy (LRT; ≥ 3 hours post-MI) significantly reduces the risk of ventricular rupture following myocardial infarction (MI), yet the structural and mechanical mechanisms behind this protection remain unclear. We hypothesized that LRT would alter the biomechanical properties of the infarct borderzone and to investigate this, we utilized laser micrometry, planar biaxial testing, and quantitative pol...

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Literature Corpus work: f3eb077d-877c-50f4-8045-4aa3bec5f9b1
DOI: 10.1101/2025.09.02.673841

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