Article
Conserved NPPB + Border Zone Switches From MEF2- to AP-1–Driven Gene Program
1 Jul 2019
Abstract excerpt
BACKGROUND: Surviving cells in the postinfarction border zone are subjected to intense fluctuations of their microenvironment. Recently, border zone cardiomyocytes have been specifically implicated in cardiac regeneration. Here, we defined their unique transcriptional and regulatory properties, and comprehensively validated new molecular markers, including Nppb, encoding B-type natriuretic peptide, after...
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