Article

Cross-trait assortative mating is widespread and inflates genetic correlation estimates

2022-03-23

Abstract excerpt

The observation of genetic correlations between disparate traits has been interpreted as evidence of widespread pleiotropy, altered theories of human genetic architecture, and spurred considerable research activity across the natural and social sciences. Here, we introduce cross-trait assortative mating (xAM) as an alternative explanation for observed genetic correlations. We observe that xAM is common across a br...

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Literature Corpus work: eb8ea50a-c1c8-5212-b2c6-0847ecd43eed
DOI: 10.1101/2022.03.21.485215

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