Article

Identification of a novel <i>CLPX</i> variant in a mixed breed dog with anemia and spinocerebellar ataxia

2025-09-18

Abstract excerpt

Spinocerebellar ataxia (SCA) or hereditary ataxia is a progressive neurodegenerative disorder primarily manifesting as cerebellar or spinocerebellar dysfunction, resulting in the loss of motor control and voluntary muscle coordination. SCAs are typically inherited conditions, with causative genetic variants identified in multiple genes in people and across various dog breeds. Recently, an atypical case of SCA was...

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Literature Corpus work: eb655805-ac25-5d7d-93a7-453b84f03225
DOI: 10.1101/2025.09.15.676223

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