Article

Dissociation of tic generation from tic expression during the sleep-wake cycle

2020-06-29

Abstract excerpt

Motor tics, the hallmark of Tourette syndrome, are modulated by different behavioral and environmental factors. A major modulating factor is the sleep-wake cycle in which tics are attenuated to a large extent during sleep. This study demonstrates a similar reduction in tic expression during sleep in an animal model of chronic tic disorders and investigates the underlying neural mechanism. We recorded the neuronal...

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Literature Corpus work: eb58c6e2-dbb8-5412-8167-02c737e3f5c8
DOI: 10.1101/2020.06.29.176974

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