Article

Expression of Unfolded Protein Response Genes in Post-transplantation Liver Biopsies

2022-02-23

Abstract excerpt

Cholestatic liver diseases are a major source of morbidity and mortality that can progress to end-stage liver disease. There are few effective medical therapies for primary biliary cholangitis, primary sclerosing cholangitis and other cholestatic liver diseases, in part, due to our incomplete understanding of the pathogenesis of cholestatic liver injury. The hepatic unfolded protein response (UPR) is an adaptive c...

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Literature Corpus work: eb28350f-2d3d-569b-a3fd-9dde019c870e
DOI: 10.1101/2022.02.21.480553

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