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Article

The role of cholangiocytes in the prediction and detection of drug-induced liver injury

2019-01-01

Abstract excerpt

Drug-induced liver injury (DILI) is a leading cause of drug attrition throughout all stages of the drug discovery process and is a frequent adverse drug reaction (ADR) with significant clinical burden. Therefore, a concerted effort to predict the onset of DILI before clinical manifestation is paramount. Nevertheless, currently available models to predict DILI are often lacking, due to their poor physiological rele...

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Literature Corpus work
7321fc10-fe45-58f6-9041-c8f46067894a
DOI
10.17638/03061355
Open publication

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