Article

Nuclear Factor I genes drive chondrogenic cell-fate commitment

2026-04-22

Abstract excerpt

Human induced pluripotent stem cells (hiPSCs) offer a powerful platform to model chondrogenesis and enable regenerative strategies, yet regulation of cell-fate commitment remains elusive. Here, we systematically mapped cell-fate trajectories from 7 time points during a 49-day chondrogenic hiPSC differentiation protocol using single-nucleus multimodal transcriptomic and chromatin accessibility profiling (scRNA-seq...

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Literature Corpus work: eb0f2157-2799-5bcc-8dd4-25beb5205203
DOI: 10.64898/2026.04.21.719911

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