Article

Integration of behavioral and biological variables using penalized regression: an application to the maternal immune activation model of autism

2020-03-31

Abstract excerpt

Maternal immune activation (MIA) during pregnancy increases the odds of developing neuropsychiatric disorders such as autism spectrum disorder (ASD) later in life. In pregnant mice, MIA can be induced by injecting the viral mimic polyinosinic:polycytidylic acid (poly(I:C) to pregnant dams resulting in altered fetal neurodevelopmental and behavioral changes in their progeny. Although the murine MIA model has been e...

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Literature Corpus work: eadde037-c31b-5442-a938-d79ccd214b9b
DOI: 10.1101/2020.03.31.018333

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