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Article

The role of the kynurenine pathway in the pathophysiology of autism-like phenotype induced by maternal inflammation in male mice.

Neurobiology of disease - 1 Mar 2026

Santana-Coelho Danielle, Dos Santos de Bessa Rafael, Romcy-Pereira Rodrigo Neves, de la Flor Miguel A, O'Connor Jason C

Abstract excerpt

Autism spectrum disorder (ASD) is a neurodevelopmental disorder with core symptoms that may include deficits in communication, social challenges, and repetitive/stereotyped behavior. The etiology of ASD is not well defined, but both genetic and environmental risk factors have been identified. In animal models, prenatal maternal immune activation precipitates the development of a behavioral phenotype resembling...

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Identifiers

PMID: 41577052
DOI: 10.1016/j.nbd.2026.107282
PMCID: PMC13367314

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MIA
IDO1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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