Article

Interneuron loss and microglia activation by transcriptome analyses in the basal ganglia of Tourette syndrome

2024-02-28

Abstract excerpt

Tourette syndrome (TS) is a disorder of high-order integration of sensory, motor, and cognitive functions afflicting as many as 1 in 150 children and characterized by motor hyperactivity and tics. Despite high familial recurrence rates, a few risk genes and no biomarkers have emerged as causative or predisposing factors. The syndrome is believed to originate in basal ganglia, where patterns of motor programs are e...

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Literature Corpus work: eacb103b-bc25-5960-a67b-daf23b34b4a7
DOI: 10.1101/2024.02.28.582504

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