Article

Antagonism between regular and atypical Cxcr3 receptors regulates macrophage migration during infection and injury in zebrafish

2019-07-31

Abstract excerpt

The CXCR3-CXCL11 chemokine-signaling axis plays an essential role in infection and inflammation by orchestrating leukocyte trafficking in human and animal models, including zebrafish. Atypical chemokine receptors (ACKRs) play a fundamental regulatory function in signaling networks by shaping chemokine gradients through their ligand scavenging function, while being unable to signal in the classic G-protein-dependen...

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Literature Corpus work: eabc8bed-7eb8-5f17-a771-a744c44fdf01
DOI: 10.1101/719526

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