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Article

The Role of the CXCL12/CXCR4/ACKR3 Axis in Autoimmune Diseases

27 Aug 2019

Abstract excerpt

Chemokine receptors are members of the G protein-coupled receptor superfamily. These receptors are intimately involved in cell movement, and thus play a critical role in several physiological and pathological situations that require the precise regulation of cell positioning. CXCR4 is one of the most studied chemokine receptors and is involved in many functions beyond leukocyte recruitment. During embryogenesis,...

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Identifiers

PMID: 31507535
DOI: 10.3389/fendo.2019.00585

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