Release of extraction-resistant mRNA in stationary phase Saccharomyces cerevisiae produces a massive increase in transcript abundance in response to stress.

Abstract excerpt

BACKGROUND: As carbon sources are exhausted, Saccharomyces cerevisiae cells exhibit reduced metabolic activity and cultures enter the stationary phase. We asked whether cells in stationary phase cultures respond to additional stress at the level of transcript abundance. RESULTS: Microarrays were used to quantify changes in transcript abundance in cells from stationary phase cultures in response to stress. More...

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