Article

Quantitative Analysis of Drug Efficacy on <i>C. elegans</i> Models for Neuromuscular Diseases

2021-01-21

Abstract excerpt

Caenorhabditis elegans has emerged as a powerful model organism for drug screening due to its cellular simplicity, genetic amenability and homology to humans combined with its small size and low cost. Currently, high-throughput drug screening assays are mostly based on image-based phenotyping not exploiting key locomotory parameters of this multicellular model with muscles such as its thrashing force, a critical p...

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Literature Corpus work: eab36953-54a6-5aea-ba9d-1b3879523d15
DOI: 10.1101/2021.01.21.427562

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