Article
Diagnosis, treatment, and follow-up of medullary thyroid carcinoma: recommendations by the Thyroid Department of the Brazilian Society of Endocrinology and Metabolism.
Arquivos brasileiros de endocrinologia e metabologia - 1 Oct 2014
Maia Ana Luiza, Siqueira Debora R, Kulcsar Marco A V, Tincani Alfio J, Mazeto Glaucia M F S, Maciel Lea M Z
Abstract excerpt
INTRODUCTION: Medullary thyroid carcinoma (MTC) originates in the thyroid parafollicular cells and represents 3-4% of the malignant neoplasms that affect this gland. Approximately 25% of these cases are hereditary due to activating mutations in the REarranged during Transfection (RET) proto-oncogene. The course of MTC is indolent, and survival rates depend on the tumor stage at diagnosis. The present article...
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