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Article

Identification of a potential non-coding RNA biomarker signature for amyotrophic lateral sclerosis

1 Jan 2020

Abstract excerpt

Objective biomarkers for the clinically heterogeneous adult-onset neurodegenerative disorder amyotrophic lateral sclerosis are crucial to facilitate assessing emerging therapeutics and improve the diagnostic pathway in what is a clinically heterogeneous syndrome. With non-coding RNA transcripts including microRNA, piwi-RNA and transfer RNA present in human biofluids, we sought to identify whether non-coding RNA...

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PMID: 32613197
DOI: 10.1093/braincomms/fcaa053

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