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Integration of Single-Cell RNA Sequencing and Bulk RNA Sequencing Data to Establish and Validate a Prognostic Model for Patients With Lung Adenocarcinoma

27 Jan 2022

Abstract excerpt

Background: Lung adenocarcinoma (LUAD) remains a lethal disease worldwide, with numerous studies exploring its potential prognostic markers using traditional RNA sequencing (RNA- seq ) data. However, it cannot detect the exact cellular and molecular changes in tumor cells. This study aimed to construct a prognostic model for LUAD using single-cell RNA- seq (scRNA- seq ) and traditional RNA- seq data. Methods:...

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PMID: 35154287
DOI: 10.3389/fgene.2022.833797

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