Telomere-related gene risk model for prognosis and drug treatment efficiency prediction in esophageal carcinoma

Abstract excerpt

<title>Abstract</title> <p>Background As the telomere functions continued to be unraveled, we aim to develop a prognostic gene signature that telomere-related features for patients with esophageal carcinoma. Methods First, differentially expressed genes (DEGs) related to telomere in ESCA were detected, Based on telomere-related DEGs, variables were determined by the LASSO regression and multivariate Cox, and a pr...

Topics

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• Autophagy in Disease and Therapy
• Cancer Immunotherapy and Biomarkers
• Esophageal Cancer Research and Treatment
• Ferroptosis and cancer prognosis
• Pancreatic and Hepatic Oncology Research
• Telomeres, Telomerase, and Senescence

Identifiers and source

Literature Corpus work

a2ad0a2b-d3d5-5f8f-a453-459ca293370b

DOI

10.21203/rs.3.rs-4028429/v1