Back to search

Article

Development of a Novel Anoikis-Related Prognostic Signature and Validation of CD36 as a Potential Target for Reversing 5-FU Resistance in Gastric Cancer

2026-05-04

Abstract excerpt

<title>Abstract</title> <p>Background Gastric cancer (GC) remains a leading cause of cancer-related mortality, with chemoresistance and metastasis being primary hurdles to effective treatment. Anoikis resistance is a critical survival mechanism enabling tumor dissemination; however, the cellular heterogeneity of anoikis-related genes and their specific roles in remodeling the tumor microenvironment (TME) and med...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
ea368a2b-9403-5e33-8754-0227610f70ff
DOI
10.21203/rs.3.rs-9403650/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Development of a Novel Anoikis-Related Prognostic Signature and Validation of CD36 as a Potential Target for Reversing 5-FU Resistance in Gastric CancerDOI 10.21203/rs.3.rs-9403650/v1
A Stromal-Immune Gene Signature for Precision Prognosis and Therapeutic Guidance in Gastric CancerSemantic proximity
Combined scRNA-seq and bulk transcriptome analysis establishes a stromal signature for predicting prognosis and therapeutic sensitivity in gastric cancerSemantic proximity
Profiling Cancer-Associated Fibroblasts (CAFs) in Gastric Cancer and Development of a CAF-Based Prognostic Signature Using Integrated Single-Cell RNA Sequencing and TCGA AnalysisSemantic proximity
A novel anoikis-related prognostic signature associated with prognosis and immune infiltration landscape in colorectal cancerSemantic proximity
Comprehensive bioinformatic analysis reveals a cancer-associated fibroblast gene signature as a poor prognostic factor and potential therapeutic target in gastric cancerSemantic proximity
COL5A2 is a prognostic-related biomarker and correlated with immune infiltrates in gastric cancer based on transcriptomics and single-cell RNA sequencingSemantic proximity
Exploring the prognostic value of N4-acetylcytosine- modified genes in colorectal cancer using transcriptomics combined with single-cell dataSemantic proximity
Exploration and experimental verification of triaptosis-related prognostic genes and cells in gastric cancerSemantic proximity
Representing ECM composition and EMT pathways in gastric cancer using a new metastatic gene signatureSemantic proximity
Construction of a hypoxia-immune-related prognostic panel based on integrated single-cell and bulk RNA sequencing analyses in gastric cancerSemantic proximity
Comprehensive immunophenotyping of gastric adenocarcinoma identifies an inflamed class of tumors amenable to immunotherapiesSemantic proximity
Integrative single-cell and spatial transcriptomics uncover ELK4-mediated mechanisms in NDUFAB1+ tumor cells driving gastric cancer progression, metabolic reprogramming, and immune evasionSemantic proximity
Select a neighboring publication to make it the new centre.