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Representing ECM composition and EMT pathways in gastric cancer using a new metastatic gene signature

4 Nov 2024

Abstract excerpt

Introduction Gastric cancer (GC) is an aggressive and heterogeneous malignancy marked by cellular and molecular diversity. In GC, cancer cells invade locally in the stomach at stage I and can progress to metastasis in distant organs by stage IV, where it often becomes fatal. Methods We analyzed gene expression profiles from 719 stage I and stage IV GC patients across seven public datasets, conducting functional...

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PMID: 39563861
DOI: 10.3389/fcell.2024.1481818

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