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Combined scRNA-seq and bulk transcriptome analysis establishes a stromal signature for predicting prognosis and therapeutic sensitivity in gastric cancer

2024-03-14

Abstract excerpt

<title>Abstract</title> <p>Gastric cancer (GC) is a major disease threatening human health. Tumor stroma component, mainly including fibroblasts, pericytes and endothelial cells (ECs), play a prominent role in tumor progression. This study wanted to establish a stromal prognostic signature for GC patients. Published single-cell RNA sequencing (scRNA-seq) and bulk gene expression data were obtained from Gene Expre...

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Literature Corpus work
dbba5bb0-7165-59e9-85f7-0f4cd39a4202
DOI
10.21203/rs.3.rs-3996638/v1
Open publication

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Combined scRNA-seq and bulk transcriptome analysis establishes a stromal signature for predicting prognosis and therapeutic sensitivity in gastric cancerDOI 10.21203/rs.3.rs-3996638/v1
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