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Profiling Cancer-Associated Fibroblasts (CAFs) in Gastric Cancer and Development of a CAF-Based Prognostic Signature Using Integrated Single-Cell RNA Sequencing and TCGA Analysis

2024-03-13

Abstract excerpt

<h4>Background: </h4> Cancer-associated fibroblasts (CAFs) play critical roles in tumor growth, angiogenesis, metastasis, and therapy resistance. This study aimed to investigate the characteristics of CAFs in gastric cancer (GC) and develop a CAF-based risk signature for predicting the prognosis of GC patients. <h4>Methods: </h4>: Single-cell RNA sequencing (scRNA-seq) data were obtained from the GEO database. Th...

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Literature Corpus work
83128979-93cc-57eb-a7f2-3e2c4f615dd3
DOI
10.21203/rs.3.rs-4021311/v1
Open publication

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Profiling Cancer-Associated Fibroblasts (CAFs) in Gastric Cancer and Development of a CAF-Based Prognostic Signature Using Integrated Single-Cell RNA Sequencing and TCGA AnalysisDOI 10.21203/rs.3.rs-4021311/v1
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